There is a mysterious and loud radio signal known as 'the space roar' that has yet to be explained.
15
In 1987, a Chicago TV station had its broadcast interrupted by a pirate signal that shows a man in a Max Headroom mask mumbling and being spanked with a fly swatter. Despite investigations by the FCC and FBI, this became the only known incident in which a hacker interrupted a major TV broadcast without getting caught.
19
There's a mysterious dwarf planet between Mars and Jupiter called 'Ceres' which has never been visited by spacecraft or photographed in detail, however, Earth-bound telescopes reveal a large bright shining spot on the surface of this planet, the origin and nature of which are unknown.
5
In 1518, a "dancing plague" struck Strasbourg, Alsace, whereby hundreds of people danced fervently in the streets over the period of a month. Some suffered heart attacks or strokes, and many others died from sheer exhaustion. It remains unexplained.
19